Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 17/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20653064 | 0.84 | P2RX3 (0.44) | P2RX3ALDH1A1MAPTSMN1; SMN2HIF1A | |
| SCHEMBL22105367 | 0.83 | P2RX3 (0.43) | P2RX3ALDH1A1MAPTSMN1; SMN2HIF1A | |
| SCHEMBL20652775 | 0.83 | P2RX3 (0.45) | P2RX3ALDH1A1MAPTSMN1; SMN2HIF1A | |
| SCHEMBL20653053 | 0.81 | P2RX3 (0.44) | P2RX3ALDH1A1MAPTSMN1; SMN2HIF1A | |
| SCHEMBL22105591 | 0.79 | P2RX3 (0.40) | P2RX3ALDH1A1MAPTSMN1; SMN2HIF1A | |
| SCHEMBL20656216 | 0.79 | P2RX3 (0.40) | P2RX3ALDH1A1MAPTSMN1; SMN2HIF1A | |
| SCHEMBL22105826 | 0.79 | P2RX3 (0.40) | P2RX3ALDH1A1MAPTSMN1; SMN2HIF1A | |
| SCHEMBL24095610 | 0.79 | P2RX3 (0.42) | P2RX3ALDH1A1MAPTSMN1; SMN2HIF1A | |
| SCHEMBL22105589 | 0.79 | P2RX3 (0.40) | P2RX3ALDH1A1MAPTSMN1; SMN2HIF1A | |
| SCHEMBL22105479 | 0.78 | P2RX3 (0.39) | P2RX3ALDH1A1MAPTSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652176-B1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2021-12-15 | — | — | EP | disclosed |