Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.36 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FURIN | P09958 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26560488 | 0.94 | FAP (0.39) | FAPSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL25564557 | 0.93 | FAP (0.38) | FAPSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL21082516 | 0.92 | FAP (0.39) | FAPSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL25833845 | 0.92 | FAP (0.40) | FAPSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL24584968 | 0.87 | FAP (0.39) | FAPSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL24774254 | 0.87 | FAP (0.39) | FAPSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL26140860 | 0.87 | FAP (0.39) | FAPSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL23189216 | 0.87 | FAP (0.39) | FAPSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL22525021 | 0.87 | SIRT2 (0.39) | FAPSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL22871647 | 0.86 | FAP (0.38) | FAPSIRT2SIRT1SIRT3SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021250418-A1 | TREATMENT OF DISEASES CHARACTERIZED BY OVEREXPRESSION OF ERYTHROPOIETIN-PRODUCING HEPATOCELLULAR RECEPTOR A2 (EPHA2) | BICYCLETX LIMITED (GB) | 2021-12-16 | — | — | WO | disclosed |