Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1633916 | 0.85 | ECE1 (0.38) | ECE1PDCD1LG2CD274HDAC2ALDH1A1 | |
| SCHEMBL24729188 | 0.82 | MAPT (0.40) | HDAC2 | |
| SCHEMBL8229032 | 0.79 | ECE1 (0.40) | ECE1PDCD1LG2CD274 | |
| SCHEMBL25556364 | 0.79 | ECE1 (0.40) | ECE1PDCD1LG2CD274 | |
| SCHEMBL24543149 | 0.78 | SPHK1 (0.36) | HDAC2POLB | |
| SCHEMBL18902807 | 0.78 | ECE1 (0.37) | ECE1HDAC2ALDH1A1POLB | |
| SCHEMBL26300607 | 0.76 | ECE1 (0.36) | ECE1PDCD1LG2CD274HDAC2ALDH1A1 | |
| SCHEMBL12234245 | 0.76 | ECE1 (0.36) | ECE1PDCD1LG2CD274HDAC2ALDH1A1 | |
| SCHEMBL24915343 | 0.74 | ECE1 (0.44) | ECE1PDCD1LG2CD274ALDH1A1 | |
| SCHEMBL992850 | 0.74 | ECE1 (0.44) | ECE1PDCD1LG2CD274ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252640-A1 | ASPARAGINE DERIVATIVES AND METHODS OF USING SAME | SENDA BIOSCIENCES, INC. (US) | 2021-12-16 | — | — | WO | disclosed |