Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 7/20 | 0.37 |
| ▸ | MMP3 | P08254 | 6/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13599664 | 0.84 | MAPT (0.40) | MAPTMMP2MMP3SLC22A6SMN1; SMN2 | |
| SCHEMBL24096004 | 0.82 | ECE1 (0.38) | HDAC2 | |
| SCHEMBL24543149 | 0.79 | SPHK1 (0.36) | HDAC2 | |
| SCHEMBL277723 | 0.79 | BMP1 (0.46) | MMP2MMP3SLC22A6MMP1MMP7 | |
| SCHEMBL14341832 | 0.77 | ADAMTS4 (0.53) | MAPTMMP2MMP3HDAC2 | |
| SCHEMBL16941949 | 0.75 | MAPT (0.42) | MAPTMMP2MMP3SLC22A6SMN1; SMN2 | |
| SCHEMBL19776035 | 0.73 | ECE1 (0.43) | MAPTMMP2MMP3SLC22A6SMN1; SMN2 | |
| SCHEMBL22369843 | 0.73 | MAPT (0.41) | MAPTMMP2MMP3SLC22A6SMN1; SMN2 | |
| SCHEMBL18272869 | 0.73 | MAPT (0.41) | MAPTMMP2MMP3SLC22A6SMN1; SMN2 | |
| SCHEMBL11956575 | 0.73 | GNPAT (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022160156-A1 | LIGASE FUSION PROTEINS AND APPLICATIONS THEREOF | GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) | 2022-08-04 | — | — | WO | disclosed |