Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464347 | 0.80 | EPHX2 (0.70) | EPHX2GAAHDAC8KDM1AMAOB | |
| SCHEMBL3287288 | 0.80 | EPHX2 (0.70) | EPHX2GAAHDAC8NFKB1NFKB2 | |
| SCHEMBL464351 | 0.79 | EPHX2 (1.00) | EPHX2GAAHDAC8KDM1AMAOB | |
| SCHEMBL4988882 | 0.78 | EPHX2 (0.47) | EPHX2GAANFKB1NFKB2RELA | |
| SCHEMBL4988872 | 0.78 | EPHX2 (0.47) | EPHX2GAANFKB1NFKB2RELA | |
| SCHEMBL461147 | 0.77 | EPHX2 (0.65) | EPHX2HDAC8CTSK | |
| SCHEMBL12894150 | 0.77 | EPHX2 (0.65) | EPHX2GAAHDAC8KDM1AMAOB | |
| SCHEMBL30767948 | 0.77 | EPHX2 (0.73) | EPHX2GAAHDAC8NFKB1NFKB2 | |
| SCHEMBL20803979 | 0.75 | EPHX2 (0.80) | EPHX2GAANFKB1NFKB2RELA | |
| SCHEMBL31552619 | 0.75 | EPHX2 (0.59) | EPHX2HDAC8KDM1AMAOBPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249417-A1 | HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2021-12-16 | — | — | WO | disclosed |