Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096632 | 0.84 | FNTA (0.32) | EPHX2PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL24096786 | 0.84 | CNR1 (0.31) | EPHX2MAPK8CNR1CNR2 | |
| SCHEMBL24096628 | 0.84 | USP30 (0.42) | BRD4PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL24096827 | 0.83 | PIM1 (0.41) | BRD4PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL24096729 | 0.83 | PIM1 (0.38) | BRD4CREBBPPIM1MARK3MAP4K2 | |
| SCHEMBL24096727 | 0.83 | PIM1 (0.38) | BRD4CREBBPPIM1MARK3MAP4K2 | |
| SCHEMBL24096850 | 0.81 | PIM1 (0.36) | BRD4CREBBPPIM1MARK3MAP4K2 | |
| SCHEMBL24096848 | 0.81 | PIM1 (0.36) | BRD4CREBBPPIM1MARK3MAP4K2 | |
| SCHEMBL24096774 | 0.80 | L3MBTL1 (0.38) | BRD4CREBBPPIM1MARK3MAP4K2 | |
| SCHEMBL24096828 | 0.78 | PIM1 (0.42) | BRD4CREBBPPIM1MARK3MAP4K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249417-A1 | HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2021-12-16 | — | — | WO | disclosed |