Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096869 | 0.82 | HDAC4 (0.46) | USP30HDAC4HDAC6TRPV1PIM1 | |
| SCHEMBL24096892 | 0.82 | HDAC4 (0.46) | USP30HDAC4HDAC6TRPV1PIM1 | |
| SCHEMBL24096725 | 0.80 | CDK2 (0.47) | USP30HDAC4HDAC6PIM1PIM2 | |
| SCHEMBL17927228 | 0.74 | KMT2A (0.59) | USP30HDAC4HDAC6TRPV1PHGDH | |
| SCHEMBL30028550 | 0.74 | KMT2A (0.59) | USP30HDAC4HDAC6TRPV1PHGDH | |
| SCHEMBL24781306 | 0.74 | KMT2A (0.59) | USP30HDAC4HDAC6TRPV1PHGDH | |
| SCHEMBL1467081 | 0.74 | USP30 (0.53) | USP30HDAC4HDAC6PIM1PIM2 | |
| SCHEMBL24096795 | 0.73 | USP30 (0.42) | USP30HDAC4HDAC6TRPV1PIM1 | |
| SCHEMBL24096835 | 0.72 | JAK3 (0.41) | USP30HDAC4HDAC6TRPV1PIM1 | |
| SCHEMBL24096838 | 0.72 | JAK3 (0.41) | USP30HDAC4HDAC6TRPV1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249417-A1 | HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2021-12-16 | — | — | WO | disclosed |