SCHEMBL24096869 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	HDAC4	P56524	2/20	0.46

▸	HDAC6	Q9UBN7	2/20	0.46

▸	TRPV1	Q8NER1	1/20	0.43

▸	USP30	Q70CQ3	5/20	0.41

▸	PIM1	P11309	2/20	0.40

▸	PIM2	Q9P1W9	2/20	0.40

▸	PARP1	P09874	1/20	0.40

▸	FPR3	P25089	1/20	0.40

▸	FPR2	P25090	1/20	0.40

▸	PBK	Q96KB5	1/20	0.39

▸	BTK	Q06187	2/20	0.39

▸	ADORA1	P30542	1/20	0.38

▸	IDH1	O75874	1/20	0.38

▸	ANO1	Q5XXA6	1/20	0.37

▸	PIK3CD	O00329	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24096892	1.00	HDAC4 (0.46)	HDAC4HDAC6TRPV1USP30PIM1
SCHEMBL24096795	0.88	USP30 (0.42)	HDAC4HDAC6TRPV1USP30PIM1
SCHEMBL24096718	0.85	HDAC4 (0.34)	HDAC4HDAC6USP30FPR3FPR2
SCHEMBL24096721	0.85	HDAC4 (0.34)	HDAC4HDAC6USP30FPR3FPR2
SCHEMBL24096766	0.84	HDAC4 (0.45)	HDAC4HDAC6TRPV1USP30PIM1
SCHEMBL24096728	0.83	MAPK8 (0.35)	HDAC4HDAC6USP30IDH1
SCHEMBL24096714	0.83	MAPK8 (0.35)	HDAC4HDAC6USP30IDH1
SCHEMBL24096739	0.82	BTK (0.46)	HDAC4HDAC6USP30PIM1PIM2
SCHEMBL24096735	0.82	BTK (0.46)	HDAC4HDAC6USP30PIM1PIM2
SCHEMBL24096891	0.82	USP30 (0.45)	HDAC4HDAC6TRPV1USP30PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021249417-A1	HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF	赛诺哈勃药业（成都）有限公司	2021-12-16	—	—	WO	disclosed