Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24098360 | 0.88 | MEN1 (0.48) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13333434 | 0.76 | MEN1 (0.55) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1854707 | 0.76 | MEN1 (0.55) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9531242 | 0.72 | MEN1 (0.62) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24582613 | 0.71 | MEN1 (0.44) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24582014 | 0.70 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16927514 | 0.70 | MAPT (0.50) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16927515 | 0.70 | MAPT (0.50) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3567792 | 0.70 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13316003 | 0.70 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249533-A1 | ESTROGEN RECEPTOR MODULATOR COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2021-12-16 | — | — | WO | disclosed |