Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1854707 | 1.00 | MEN1 (0.55) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL9531242 | 0.82 | MEN1 (0.62) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL874981 | 0.80 | MEN1 (0.55) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL837741 | 0.80 | MEN1 (0.55) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL468399 | 0.79 | MEN1 (0.68) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL29629485 | 0.79 | MEN1 (0.68) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4628084 | 0.79 | MEN1 (0.58) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL24098360 | 0.79 | MEN1 (0.48) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3800701 | 0.78 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3800702 | 0.78 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338473-B2 | Derivatives of psammaplin A, a method for their synthesis and their uses for the prevention or treatment of cancer | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-12-25 | — | — | US | disclosed |
| US-20100120885-A1 | Novel Derivatives of Psammaplin A, A Method For Their Synthesis And Their Uses For The Prevention Or Treatment Of Cancer | RADBOUND UNIVERSITY NIJMEGEN (NL) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120885-A1 | Novel Derivatives of Psammaplin A, A Method For Their Synthesis And Their Uses For The Prevention Or Treatment Of Cancer | PSAP, PSAT1, SPAG5 | MEN1 1036/4885KMT2A 3858/4885ALDH1A1 2602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.