Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 3/20 | 0.36 |
| ▸ | CDK8 | P49336 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28971440 | 1.00 | HDAC1 (0.42) | HDAC1HDAC8HDAC6IDO1TDO2 | |
| SCHEMBL24098560 | 0.83 | HDAC1 (0.61) | HDAC1HDAC8HDAC6CYP3A4 | |
| SCHEMBL24099413 | 0.83 | IDO1 (0.47) | HDAC1HDAC8HDAC6IDO1TDO2 | |
| SCHEMBL28971429 | 0.83 | IDO1 (0.47) | HDAC1HDAC8HDAC6IDO1TDO2 | |
| SCHEMBL28971434 | 0.82 | IDO1 (0.45) | HDAC1HDAC8HDAC6IDO1TDO2 | |
| SCHEMBL25889700 | 0.82 | IDO1 (0.45) | HDAC1HDAC8HDAC6IDO1TDO2 | |
| SCHEMBL24098880 | 0.79 | IDO1 (0.43) | HDAC1HDAC8HDAC6IDO1TDO2 | |
| SCHEMBL28971447 | 0.79 | IDO1 (0.43) | HDAC1HDAC8HDAC6IDO1TDO2 | |
| SCHEMBL24099276 | 0.77 | POLB (0.41) | HDAC1HDAC8HDAC6KCNH2HRH3 | |
| SCHEMBL24098960 | 0.76 | IDO1 (0.50) | HDAC1HDAC8HDAC6IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161908-B1 | QUINAZOLINE DERIVATIVES USEFUL AS SELECTIVE HDAC6 INHIBITORS | ANNJI PHARM CO LTD (TW) | 2026-04-01 | — | — | EP | disclosed |
| US-20230212129-A1 | QUINAZOLINE DERIVATIVES USEFUL AS SELECTIVE HDAC6 INHIBITORS | Annji Pharmaceutical Co., Ltd. (TW) | 2023-07-06 | — | — | US | disclosed |
| US-20230212129-A1 | QUINAZOLINE DERIVATIVES USEFUL AS SELECTIVE HDAC6 INHIBITORS | Annji Pharmaceutical Co., Ltd. (TW) | 2023-07-06 | — | — | US | disclosed |
| EP-4161908-A1 | QUINAZOLINE DERIVATIVES USEFUL AS SELECTIVE HDAC6 INHIBITORS | Annji Pharmaceutical Co., Ltd. (TW) | 2023-04-12 | — | — | EP | disclosed |
| WO-2021252475-A1 | QUINAZOLINE DERIVATIVES USEFUL AS SELECTIVE HDAC6 INHIBITORS | Annji Pharmaceutical Co., Ltd. (TW) | 2021-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212129-A1 | QUINAZOLINE DERIVATIVES USEFUL AS SELECTIVE HDAC6 INHIBITORS | HDAC6, HDAC1, HDAC5 | HDAC1 2/4885HDAC8 16/4885HDAC6 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.