Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 5/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24099274 | 0.88 | ALDH1A1 (0.38) | POLBL3MBTL1ALDH1A1LMNAHCAR1 | |
| SCHEMBL24098560 | 0.79 | HDAC1 (0.61) | HDAC1HDAC8HDAC6 | |
| SCHEMBL16596931 | 0.78 | PIK3CD (0.49) | L3MBTL1ALDH1A1LMNAHCAR1HRH3 | |
| SCHEMBL28971440 | 0.77 | HDAC1 (0.42) | ALDH1A1HDAC1HDAC8HDAC6HRH3 | |
| SCHEMBL24099285 | 0.77 | HDAC1 (0.42) | ALDH1A1HDAC1HDAC8HDAC6HRH3 | |
| SCHEMBL15840304 | 0.77 | POLB (0.36) | POLBL3MBTL1ALDH1A1LMNAHCAR1 | |
| SCHEMBL17449521 | 0.74 | ACSS2 (0.41) | POLBALDH1A1LMNAHSD17B10 | |
| SCHEMBL24098901 | 0.73 | L3MBTL1 (0.46) | POLBL3MBTL1ALDH1A1LMNAHRH3 | |
| SCHEMBL16596950 | 0.72 | PIK3CD (0.52) | POLBL3MBTL1HDAC1HDAC8HDAC6 | |
| SCHEMBL16596972 | 0.71 | HRH3 (0.56) | POLBL3MBTL1ALDH1A1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252475-A1 | QUINAZOLINE DERIVATIVES USEFUL AS SELECTIVE HDAC6 INHIBITORS | Annji Pharmaceutical Co., Ltd. (TW) | 2021-12-16 | — | — | WO | disclosed |