Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22226579 | 0.91 | HPGD (0.43) | USP30GRM5HPGDTSHRSMN1; SMN2 | |
| SCHEMBL24099642 | 0.90 | SMN1; SMN2 (0.42) | USP30GRM5HPGDSMN1; SMN2PIK3CA | |
| SCHEMBL24100527 | 0.90 | HPGD (0.45) | USP30GRM5HPGDTSHRRECQL | |
| SCHEMBL24101118 | 0.89 | HPGD (0.47) | USP30GRM5HPGDPIK3CAALDH1A1 | |
| SCHEMBL22227266 | 0.87 | HPGD (0.45) | USP30GRM5HPGDCRBNTSHR | |
| SCHEMBL24100180 | 0.86 | HPGD (0.39) | USP30GRM5HPGDCRBNTSHR | |
| SCHEMBL22226872 | 0.86 | USP30 (0.38) | USP30GRM5HPGDCRBNTSHR | |
| SCHEMBL22226783 | 0.85 | GRM5 (0.44) | USP30GRM5CRBNPIK3CAKMT2A | |
| SCHEMBL22227202 | 0.84 | USP30 (0.42) | USP30GRM5HPGDCRBNPIK3CA | |
| SCHEMBL24100462 | 0.83 | PIK3CA (0.37) | GRM5HPGDTSHRSMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922247-A1 | 15-PGDH INHIBITOR | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-12-15 | — | — | EP | disclosed |