SCHEMBL24101925

SCHEMBL24101925

COC(=O)C1CCC(c2ccccc2Cl)N1C(=O)c1ccc(-c2ccccc2OC)cc1

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2035325 1.00 FFAR2 (0.83) FFAR2
SCHEMBL21313770 1.00 FFAR2 (0.83) FFAR2
SCHEMBL21313769 1.00 FFAR2 (0.83) FFAR2
SCHEMBL29787656 1.00 FFAR2 (0.83) FFAR2
SCHEMBL30957220 0.91 FFAR2 (1.00) FFAR2
SCHEMBL2045666 0.91 FFAR2 (1.00) FFAR2
SCHEMBL2041981 0.91 FFAR2 (1.00) FFAR2
SCHEMBL30957219 0.91 FFAR2 (1.00) FFAR2
SCHEMBL14635146 0.91 FFAR2 (1.00) FFAR2
SCHEMBL14635496 0.91 FFAR2 (1.00) FFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021250174-A1 SYNTHESIS OF (2S,5R)-5-(2-CHLOROPHENYL)-1-(2'-METHOXY-[1,1'-BIPHENYL]-4-CARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID EPICS THERAPEUTICS (BE) 2021-12-16 WO disclosed