Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 16/20 | 0.40 |
| ▸ | ELOC | Q15369 | 10/20 | 0.40 |
| ▸ | ELOB | Q15370 | 10/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31605674 | 0.89 | VHL (0.40) | VHLELOCELOBDPP4DPP8 | |
| SCHEMBL21350058 | 0.87 | VHL (0.40) | VHLELOCELOB | |
| SCHEMBL24621246 | 0.86 | VHL (0.40) | VHLELOCELOBDPP4DPP8 | |
| SCHEMBL31605683 | 0.85 | VHL (0.41) | VHLELOCELOB | |
| SCHEMBL22790711 | 0.85 | VHL (0.44) | VHLELOCELOBDPP4DPP8 | |
| SCHEMBL20111504 | 0.85 | VHL (0.44) | VHLELOCELOBDPP4DPP8 | |
| SCHEMBL21350156 | 0.84 | VHL (0.47) | VHLELOCELOB | |
| SCHEMBL21759392 | 0.84 | VHL (0.47) | VHLELOCELOB | |
| SCHEMBL26725347 | 0.84 | DPP4 (0.36) | VHLELOCELOBDPP4DPP8 | |
| SCHEMBL24262637 | 0.82 | DPP4 (0.39) | VHLELOCELOBDPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252666-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2021-12-16 | — | — | WO | disclosed |