⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145695 | 0.97 | — | — | |
| SCHEMBL60851 | 0.97 | — | — | |
| SCHEMBL31606918 | 0.94 | — | — | |
| SCHEMBL778019 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL32685341 | 0.94 | ALDH1A1 (0.50) | — | |
| Bromide SCHEMBL10615476 | 0.94 | — | — | |
| SCHEMBL778018 | 0.94 | — | — | |
| Methane SCHEMBL250227 | 0.94 | — | — | |
| SCHEMBL10919241 | 0.94 | — | — | |
| SCHEMBL780354 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367837-B1 | 1'-SUBSTITUTED RIBOSE 5'-POLYPHOSPHATE ANALOGS AND THEIR USE AS MODULATORS OF P2Y RECEPTOR ACTIVITY | MICRODOSE THERAPEUTX INC (US) | 2016-08-17 | — | — | EP | disclosed |
| US-20160129036-A1 | ADENOSINE ANALOGS AND THEIR USE | MICRODOSE THERAPEUTX INC (US) | 2016-05-12 | — | — | US | disclosed |
| US-9255121-B2 | Adenosine analogs and their use | MICRODOSE THERAPEUTX, INC. (US) | 2016-02-09 | — | — | US | disclosed |
| US-20140038912-A1 | ADENOSINE ANALOGS AND THEIR USE | MICRODOSE THERAPEUTX, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-8569259-B2 | Adenosine analogs and their use | MICRODOSE THERAPEUTX, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20110237529-A1 | Adenosine Analogs and Their Use | MICRODOSE THERAPEUTX, INC | 2011-09-29 | — | — | US | disclosed |
| EP-2367837-A2 | 1'-SUBSTITUTED RIBOSE 5'-POLYPHOSPHATE ANALOGS AND THEIR USE AS MODULATORS OF P2Y RECEPTOR ACTIVITY | MicroDose Therapeutx, Inc. (US) | 2011-09-28 | — | — | EP | disclosed |
| WO-2008060632-A2 | ADENOSINE ANALOGS AND THEIR USE | EPIX DELAWARE, INC. (US) | 2008-05-22 | — | — | WO | disclosed |