Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25816065 | 0.89 | CYP2C19 (0.30) | CYP2C19 | |
| SCHEMBL25719653 | 0.88 | EYA3 (0.34) | EYA3KDRPREPCELA1 | |
| SCHEMBL22680601 | 0.86 | EYA3 (0.39) | CYP2C19EYA3KDRPREPCELA1 | |
| SCHEMBL24266787 | 0.83 | EYA3 (0.36) | CYP2C19EYA3KDRPREPCELA1 | |
| SCHEMBL24221837 | 0.81 | CYP2C19 (0.47) | CYP2C19EYA3NR1H4 | |
| SCHEMBL24102960 | 0.78 | EYA3 (0.42) | CYP2C19EYA3NR1H4 | |
| SCHEMBL24102976 | 0.76 | CYP2C19 (0.46) | CYP2C19EYA3NR1H4 | |
| SCHEMBL20718288 | 0.75 | EYA3 (0.55) | CYP2C19EYA3NR1H4 | |
| SCHEMBL20718309 | 0.75 | EYA3 (0.44) | CYP2C19EYA3NR1H4 | |
| SCHEMBL20718353 | 0.74 | EYA3 (0.43) | CYP2C19EYA3NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252630-A1 | METHODS FOR TREATING OR PREVENTING CHRONIC KIDNEY DISEASE | ARTHROSI THERAPEUTICS, INC. (US) | 2021-12-16 | — | — | WO | disclosed |