Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 5/20 | 0.37 |
| ▸ | AKT2 | P31751 | 3/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.37 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17817658 | 1.00 | AKT1 (0.37) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL17832987 | 0.88 | AKT1 (0.40) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL17833008 | 0.85 | AKT1 (0.36) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL17817196 | 0.85 | AKT1 (0.36) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL9485449 | 0.84 | S1PR1 (0.43) | AKT1MAPK14TERTUCHL3LPAR3 | |
| SCHEMBL9485299 | 0.84 | S1PR1 (0.43) | AKT1MAPK14TERTUCHL3LPAR3 | |
| SCHEMBL17817229 | 0.82 | AKT1 (0.45) | AKT1MAPK14TERTUCHL3MEN1 | |
| SCHEMBL23016753 | 0.82 | AKT1 (0.45) | AKT1MAPK14TERTUCHL3MEN1 | |
| SCHEMBL17817209 | 0.82 | AKT1 (0.45) | AKT1MAPK14TERTUCHL3MEN1 | |
| SCHEMBL24103962 | 0.76 | LPAR3 (0.47) | LPAR3LPAR1LPAR2S1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252290-A2 | COMPOSITIONS AND METHODS FOR TREATING NOVEL CORONAVIRUS SARS-COV-2-MEDIATED INFLAMMATORY CONDITIONS | GRI BIO, INC. (US) | 2021-12-16 | — | — | WO | disclosed |