Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.31 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17817196 | 1.00 | AKT1 (0.36) | AKT1TERTUCHL3MAPK14CYP3A4 | |
| SCHEMBL17817018 | 0.90 | TERT (0.39) | AKT1TERTUCHL3MAPK14CYP3A4 | |
| SCHEMBL23016756 | 0.90 | TERT (0.39) | AKT1TERTUCHL3MAPK14CYP3A4 | |
| SCHEMBL24104635 | 0.85 | AKT1 (0.37) | AKT1TERTUCHL3MAPK14MEN1 | |
| SCHEMBL17817658 | 0.85 | AKT1 (0.37) | AKT1TERTUCHL3MAPK14MEN1 | |
| SCHEMBL17817021 | 0.79 | CYP3A4 (0.42) | AKT1TERTUCHL3MAPK14CYP3A4 | |
| SCHEMBL9485449 | 0.72 | S1PR1 (0.43) | AKT1TERTUCHL3MAPK14MEN1 | |
| SCHEMBL9485299 | 0.72 | S1PR1 (0.43) | AKT1TERTUCHL3MAPK14MEN1 | |
| SCHEMBL17832987 | 0.72 | AKT1 (0.40) | AKT1TERTUCHL3MAPK14MEN1 | |
| SCHEMBL17817223 | 0.72 | AKT1 (0.54) | AKT1TERTUCHL3MAPK14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |