SCHEMBL2410464

SCHEMBL2410464

Cc1noc(C)c1-c1cccc(O[C@@H]2SC[C@@H](O)[C@H](O)[C@H]2O)c1

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 14/20 0.51
BRD2 P25440 6/20 0.51
CREBBP Q92793 6/20 0.51
BRD3 Q15059 2/20 0.42
FFAR1 O14842 4/20 0.39
GGPS1 O95749 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2410469 1.00 BRD4 (0.51) BRD4BRD2CREBBPBRD3FFAR1
SCHEMBL2412534 0.86 SLC9A3 (0.42) BRD4BRD2CREBBP
SCHEMBL2412532 0.86 SLC9A3 (0.42) BRD4BRD2CREBBP
SCHEMBL313954 0.85 BRD4 (0.37) BRD4BRD2CREBBPFFAR1
SCHEMBL313955 0.85 BRD4 (0.37) BRD4BRD2CREBBPFFAR1
SCHEMBL315768 0.82 FFAR1 (0.37) BRD4BRD2CREBBPFFAR1
SCHEMBL315769 0.82 FFAR1 (0.37) BRD4BRD2CREBBPFFAR1
SCHEMBL2411792 0.81 EP300 (0.39) BRD4BRD2BRD3FFAR1
SCHEMBL2414234 0.81 BRD4 (0.40) BRD4BRD2CREBBPBRD3FFAR1
SCHEMBL2411789 0.81 EP300 (0.39) BRD4BRD2BRD3FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8013010-B2 5-thioxylopyranose compounds LABORATOIRES FOURNIER S.A. (FR) 2011-09-06 US disclosed
US-20090186840-A1 5-Thioxylopyranose Compounds LABORATOIRES FOURNIER S.A (FR) 2009-07-23 US disclosed
EP-2066681-A1 NEW DERIVATIVES OF 5-THIOXILOPYRANOSE LABORATOIRES FOURNIER SA (FR) 2009-06-10 EP disclosed
WO-2008037923-A1 NEW DERIVATIVES OF 5-THIOXILOPYRANOSE LABORATOIRES FOURNIER S.A. (FR) 2008-04-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090186840-A1 5-Thioxylopyranose Compounds TPMT, PNPO, CYP3A5 BRD4 4110/4885BRD2 4720/4885CREBBP 4100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.