SCHEMBL2411792

SCHEMBL2411792

Cc1noc(C)c1-c1ccc(Cl)c(O[C@H]2SC[C@@H](O)[C@H](O)[C@H]2O)c1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 2/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
FFAR1 O14842 2/20 0.39
BRD4 O60885 11/20 0.38
BRD2 P25440 5/20 0.38
BRD3 Q15059 5/20 0.38
FFAR2 O15552 1/20 0.38
ERN1 O75460 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2411789 1.00 EP300 (0.39) EP300SLC6A2SLC6A4SLC6A3FFAR1
SCHEMBL2414234 0.85 BRD4 (0.40) EP300FFAR1BRD4BRD2BRD3
SCHEMBL2414228 0.85 BRD4 (0.40) EP300FFAR1BRD4BRD2BRD3
SCHEMBL2412534 0.82 SLC9A3 (0.42) BRD4BRD2FFAR2ERN1
SCHEMBL2412532 0.82 SLC9A3 (0.42) BRD4BRD2FFAR2ERN1
SCHEMBL2412440 0.81 BRD4 (0.34) BRD4
SCHEMBL2413381 0.81 ERN1 (0.40) FFAR1BRD4ERN1
SCHEMBL2413379 0.81 ERN1 (0.40) FFAR1BRD4ERN1
SCHEMBL2412437 0.81 BRD4 (0.34) BRD4
SCHEMBL2410464 0.81 BRD4 (0.51) FFAR1BRD4BRD2BRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8013010-B2 5-thioxylopyranose compounds LABORATOIRES FOURNIER S.A. (FR) 2011-09-06 US disclosed
US-20090186840-A1 5-Thioxylopyranose Compounds LABORATOIRES FOURNIER S.A (FR) 2009-07-23 US disclosed
EP-2066681-A1 NEW DERIVATIVES OF 5-THIOXILOPYRANOSE LABORATOIRES FOURNIER SA (FR) 2009-06-10 EP disclosed
WO-2008037923-A1 NEW DERIVATIVES OF 5-THIOXILOPYRANOSE LABORATOIRES FOURNIER S.A. (FR) 2008-04-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090186840-A1 5-Thioxylopyranose Compounds TPMT, PNPO, CYP3A5 EP300 3259/4885SLC6A2 4369/4885SLC6A4 3780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.