Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410793 | 1.00 | PPARA (0.32) | PPARAPPARGPPARD | |
| SCHEMBL2416271 | 0.82 | MAPK14 (0.36) | PPARAPPARGPPARD | |
| SCHEMBL2413347 | 0.74 | PPARG (0.38) | PPARAPPARGPPARD | |
| SCHEMBL2411454 | 0.73 | PPARA (0.36) | PPARA | |
| SCHEMBL2413522 | 0.73 | HDAC1 (0.33) | PPARAPPARGPPARD | |
| SCHEMBL2418353 | 0.72 | — | — | |
| SCHEMBL2411036 | 0.71 | PPARA (0.37) | PPARAPPARG | |
| SCHEMBL2411034 | 0.71 | PPARA (0.37) | PPARAPPARG | |
| SCHEMBL2410862 | 0.71 | PPARA (0.41) | PPARAPPARGPPARD | |
| SCHEMBL12274123 | 0.71 | PPARA (0.35) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026370-B2 | Peroxisome proliferator antagonist; hyperlipemia agents; arteriosclerosis; antiischemic agents | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-09-27 | — | — | US | claimed |