Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.36 |
| ▸ | DDR2 | Q16832 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.31 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408602 | 0.90 | MAPK14 (0.39) | MAPK14DDR2PPARGPPARACTSB | |
| SCHEMBL2413912 | 0.90 | MAPK14 (0.37) | MAPK14DDR2PPARGPPARAPPARD | |
| SCHEMBL2417271 | 0.85 | PPARA (0.37) | MAPK14DDR2PPARGPPARAPPARD | |
| SCHEMBL2415495 | 0.83 | MAPK14 (0.36) | MAPK14DDR2CTSB | |
| SCHEMBL2410789 | 0.82 | PPARA (0.32) | PPARGPPARAPPARD | |
| SCHEMBL2410793 | 0.82 | PPARA (0.32) | PPARGPPARAPPARD | |
| SCHEMBL2413472 | 0.82 | MAPK14 (0.36) | MAPK14DDR2PPARGPPARAPPARD | |
| SCHEMBL2412840 | 0.82 | MAPK14 (0.36) | MAPK14DDR2PPARGPPARAPPARD | |
| SCHEMBL2413999 | 0.81 | MAPK14 (0.41) | MAPK14DDR2PPARGPPARAPPARD | |
| SCHEMBL2416901 | 0.80 | MAPK14 (0.36) | MAPK14DDR2PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026370-B2 | Peroxisome proliferator antagonist; hyperlipemia agents; arteriosclerosis; antiischemic agents | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-09-27 | — | — | US | claimed |