Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 2/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19272032 | 0.89 | CCR6 (0.43) | CCR6PAX8NPC1RAB9ASNCA | |
| SCHEMBL19018818 | 0.78 | CCR6 (0.61) | CCR6PAX8ALDH1A1KMT2AMAPK1 | |
| SCHEMBL15582141 | 0.78 | CCR6 (0.61) | CCR6PAX8ALDH1A1KMT2AMAPK1 | |
| SCHEMBL9110508 | 0.78 | CCR6 (0.61) | CCR6PAX8ALDH1A1KMT2AMAPK1 | |
| SCHEMBL16586897 | 0.77 | CCR6 (0.63) | CCR6PAX8ALDH1A1KMT2AMAPK1 | |
| SCHEMBL13485484 | 0.75 | CCR6 (0.40) | CCR6PAX8NPC1RAB9APDCD1 | |
| SCHEMBL7636570 | 0.74 | NPC1 (0.43) | CCR6NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL10822929 | 0.74 | CCR6 (0.62) | CCR6PAX8ALDH1A1KMT2AMAPK1 | |
| SCHEMBL7864948 | 0.74 | CCR6 (0.62) | CCR6PAX8ALDH1A1KMT2AMAPK1 | |
| SCHEMBL16585962 | 0.73 | CCR6 (0.60) | CCR6PAX8ALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210386845-A1 | VACCINE AGAINST KLEBSIELLA PNEUMONIAE | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210386845-A1 | VACCINE AGAINST KLEBSIELLA PNEUMONIAE | UBXN1, MLX, UBXN4 | CCR6 3609/4885PAX8 3433/4885NPC1 4538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.