Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 9/20 | 0.77 |
| ▸ | SLC16A7 | O60669 | 1/20 | 0.77 |
| ▸ | SLC16A8 | O95907 | 1/20 | 0.77 |
| ▸ | HTR5A | P47898 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Msc-4381 SCHEMBL31019750 | 0.87 | SLC16A3 (1.00) | SLC16A3SLC16A7SLC16A8HTR5APOLB | |
| Msc-4381 SCHEMBL22116621 | 0.87 | SLC16A3 (1.00) | SLC16A3SLC16A7SLC16A8HTR5APOLB | |
| SCHEMBL22116703 | 0.87 | SLC16A3 (0.89) | SLC16A3SLC16A7SLC16A8HTR5APOLB | |
| SCHEMBL30182486 | 0.86 | SLC16A3 (0.77) | SLC16A3SLC16A7SLC16A8HTR5APOLB | |
| SCHEMBL22116778 | 0.81 | SLC16A3 (0.90) | SLC16A3SLC16A7SLC16A8HTR5APOLB | |
| SCHEMBL30181890 | 0.80 | SLC16A3 (0.68) | SLC16A3SLC16A7SLC16A8HTR5APOLB | |
| SCHEMBL22116838 | 0.79 | SLC16A3 (0.76) | SLC16A3SLC16A7SLC16A8HTR5APOLB | |
| SCHEMBL22134858 | 0.79 | SLC16A3 (0.73) | SLC16A3SLC16A7SLC16A8HTR5APOLB | |
| SCHEMBL22116501 | 0.79 | SLC16A3 (0.84) | SLC16A3SLC16A7SLC16A8HTR5APOLB | |
| SCHEMBL30182206 | 0.78 | SLC16A3 (0.65) | SLC16A3SLC16A7SLC16A8HTR5APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249969-A1 | COMBINATION PRODUCT FOR THE TREATMENT OF CANCER DISEASES | MERCK PATENT GMBH (DE) | 2021-12-16 | — | — | WO | disclosed |