Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 7/20 | 0.34 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22125094 | 0.96 | KDM4E (0.37) | PTK6TTKSYKAXL | |
| SCHEMBL30349829 | 0.96 | KDM4E (0.37) | PTK6TTKSYKAXL | |
| SCHEMBL30183513 | 0.94 | PTK6 (0.36) | PTK6TTKSYKAXLMAPKAPK5 | |
| SCHEMBL30385354 | 0.94 | SYK (0.36) | PTK6TTKSYKAXLMAPKAPK5 | |
| SCHEMBL22123733 | 0.94 | TTK (0.34) | PTK6TTKSYKAXLMAPKAPK5 | |
| SCHEMBL25452733 | 0.94 | PTK6 (0.34) | PTK6TTKSYKAXLMAPKAPK5 | |
| SCHEMBL22123578 | 0.94 | SYK (0.36) | PTK6TTKSYKAXLMAPKAPK5 | |
| Hydrochloric Acid SCHEMBL25173409 | 0.94 | SYK (0.35) | PTK6TTKSYKAXLMAPKAPK5 | |
| SCHEMBL22124597 | 0.94 | SYK (0.37) | PTK6TTKSYKAXLMAPKAPK5 | |
| SCHEMBL24870783 | 0.93 | TTK (0.37) | PTK6TTKSYKAXLMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |