Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.36 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 2/20 | 0.34 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 4/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.32 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123578 | 1.00 | SYK (0.36) | SYKMAPKAPK5AXLPTK6TTK | |
| SCHEMBL22124597 | 0.99 | SYK (0.37) | SYKMAPKAPK5AXLPTK6TTK | |
| Hydrochloric Acid SCHEMBL25173409 | 0.99 | SYK (0.35) | SYKMAPKAPK5AXLPTK6TTK | |
| Hydrochloric Acid SCHEMBL22123465 | 0.99 | SYK (0.36) | SYKMAPKAPK5AXLPTK6TTK | |
| SCHEMBL22123340 | 0.95 | SYK (0.35) | SYKMAPKAPK5AXLPTK6TTK | |
| SCHEMBL24977978 | 0.95 | MAPKAPK5 (0.35) | SYKMAPKAPK5AXLPTK6TTK | |
| SCHEMBL24112091 | 0.94 | PTK6 (0.36) | SYKMAPKAPK5AXLPTK6TTK | |
| SCHEMBL22124871 | 0.94 | SYK (0.39) | SYKMAPKAPK5AXLPTK6TTK | |
| SCHEMBL22124653 | 0.94 | SYK (0.39) | SYKMAPKAPK5AXLPTK6TTK | |
| SCHEMBL22122926 | 0.94 | SYK (0.38) | SYKMAPKAPK5AXLPTK6TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |