Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 15/20 | 0.49 |
| ▸ | TTK | P33981 | 4/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.41 |
| ▸ | LCK | P06239 | 5/20 | 0.41 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22124095 | 0.93 | PTK6 (0.47) | PTK6TTKAURKBLCKMAPKAPK5 | |
| SCHEMBL22124439 | 0.92 | PTK6 (0.45) | PTK6TTKAURKBLCKMAPKAPK5 | |
| SCHEMBL22124869 | 0.92 | PTK6 (0.46) | PTK6TTKAURKBLCKMAPKAPK5 | |
| SCHEMBL22124463 | 0.92 | PTK6 (0.46) | PTK6TTKAURKBLCKMAPKAPK5 | |
| SCHEMBL22123915 | 0.92 | PTK6 (0.48) | PTK6TTKAURKBLCK | |
| SCHEMBL22124070 | 0.92 | PTK6 (0.46) | PTK6TTKAURKBLCKMAPKAPK5 | |
| Hydrochloric Acid SCHEMBL22123808 | 0.92 | PTK6 (0.46) | PTK6TTKAURKBLCKMAPKAPK5 | |
| SCHEMBL22124068 | 0.92 | PTK6 (0.46) | PTK6TTKAURKBLCKMAPKAPK5 | |
| SCHEMBL22123998 | 0.92 | PTK6 (0.51) | PTK6TTKAURKBLCK | |
| SCHEMBL22142735 | 0.91 | PTK6 (0.50) | PTK6TTKAURKBLCKMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |