Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 7/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | ZAP70 | P43403 | 5/20 | 0.33 |
| ▸ | KARS1 | Q15046 | 4/20 | 0.33 |
| ▸ | SYK | P43405 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123589 | 0.95 | TTK (0.35) | TTKZAP70KARS1SYKIDO1 | |
| SCHEMBL22124722 | 0.94 | PDE10A (0.35) | TTKZAP70KARS1SYKIDO1 | |
| SCHEMBL22124854 | 0.94 | PDE10A (0.35) | TTKZAP70KARS1SYKIDO1 | |
| SCHEMBL22124796 | 0.92 | CDK2 (0.35) | TTKZAP70KARS1PTK2 | |
| SCHEMBL30385860 | 0.92 | CDK2 (0.35) | TTKZAP70KARS1PTK2 | |
| SCHEMBL25450808 | 0.92 | TTK (0.32) | TTKZAP70KARS1SYKIDO1 | |
| SCHEMBL30171548 | 0.92 | ZAP70 (0.39) | TTKZAP70KARS1SYKIDO1 | |
| SCHEMBL22123380 | 0.92 | ZAP70 (0.39) | TTKZAP70KARS1SYKIDO1 | |
| Formic Acid SCHEMBL22123789 | 0.92 | PDE10A (0.34) | TTKZAP70KARS1SYKIDO1 | |
| SCHEMBL30171536 | 0.91 | BRD4 (0.39) | TTKZAP70IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |