Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 3/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 3/20 | 0.37 |
| ▸ | BCL6 | P41182 | 4/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24870783 | 0.92 | TTK (0.37) | PTK6POLBTTKPDE4BPDE4D | |
| SCHEMBL25450753 | 0.92 | PTK6 (0.41) | PTK6FLT1FLT4KDRBCL6 | |
| SCHEMBL22124504 | 0.91 | PTK6 (0.42) | PTK6TTKBCL6MCHR1IGF1R | |
| SCHEMBL25450752 | 0.91 | PTK6 (0.41) | PTK6TTKBCL6MCHR1LCK | |
| SCHEMBL22123532 | 0.91 | PTK6 (0.42) | PTK6TTKBCL6MCHR1IGF1R | |
| SCHEMBL22123658 | 0.91 | PTK6 (0.42) | PTK6TTKBCL6MCHR1IGF1R | |
| SCHEMBL22123365 | 0.91 | PTK6 (0.42) | PTK6TTKBCL6MCHR1IGF1R | |
| SCHEMBL25450750 | 0.91 | PTK6 (0.42) | PTK6TTKBCL6MCHR1LCK | |
| Hydrochloric Acid SCHEMBL30171699 | 0.91 | PTK6 (0.42) | PTK6TTKBCL6MCHR1IGF1R | |
| SCHEMBL22124604 | 0.90 | PTK6 (0.41) | PTK6BCL6MCHR1IGF1RSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |