Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 4/20 | 0.41 |
| ▸ | TTK | P33981 | 6/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22125051 | 0.92 | PTK6 (0.39) | PTK6TTKBRAFMAPKAPK5POLB | |
| SCHEMBL22123059 | 0.92 | PTK6 (0.39) | PTK6TTKBRAFMAPKAPK5IDO1 | |
| SCHEMBL30349820 | 0.92 | PTK6 (0.39) | PTK6TTKBRAFMAPKAPK5POLB | |
| SCHEMBL24940112 | 0.92 | PTK6 (0.39) | PTK6TTKBRAFMAPKAPK5IDO1 | |
| Hydrochloric Acid SCHEMBL25176396 | 0.92 | PTK6 (0.39) | PTK6TTKBRAFMAPKAPK5IDO1 | |
| SCHEMBL25450711 | 0.91 | PTK6 (0.38) | PTK6TTKBRAFMAPKAPK5IDO1 | |
| SCHEMBL22125019 | 0.90 | PTK6 (0.38) | PTK6TTKBRAFMAPKAPK5IDO1 | |
| SCHEMBL22124783 | 0.90 | PTK6 (0.39) | PTK6TTKBRAFMAPKAPK5IDO1 | |
| SCHEMBL25170444 | 0.89 | PTK6 (0.43) | PTK6TTKBRAFMAPKAPK5IDO1 | |
| SCHEMBL22122840 | 0.89 | KDM4E (0.42) | PTK6TTKMAPKAPK5METLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |