Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.88 |
| ▸ | S1PR3 | Q99500 | 12/20 | 0.88 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1601733 | 0.94 | S1PR1 (1.00) | S1PR1S1PR3KCNH2 | |
| SCHEMBL1602703 | 0.88 | S1PR1 (0.89) | S1PR1S1PR3KCNH2 | |
| SCHEMBL1601354 | 0.88 | S1PR1 (0.88) | S1PR1S1PR3KCNH2 | |
| SCHEMBL1601562 | 0.88 | S1PR1 (0.88) | S1PR1S1PR3KCNH2 | |
| SCHEMBL1602248 | 0.87 | S1PR1 (0.86) | S1PR1S1PR3KCNH2 | |
| SCHEMBL4443009 | 0.86 | S1PR1 (0.85) | S1PR1S1PR3KCNH2 | |
| SCHEMBL1601119 | 0.86 | S1PR1 (1.00) | S1PR1S1PR3KCNH2 | |
| SCHEMBL1601448 | 0.86 | S1PR1 (0.85) | S1PR1S1PR3KCNH2 | |
| SCHEMBL1602394 | 0.86 | S1PR1 (0.85) | S1PR1S1PR3KCNH2 | |
| SCHEMBL1602925 | 0.86 | S1PR1 (0.84) | S1PR1S1PR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364976-B1 | S1P receptor modulating compounds and use thereof | EPIX PHARM INC (US) | 2014-10-08 | — | — | EP | disclosed |
| EP-2364976-A1 | S1P receptor modulating compounds and use thereof | EPIX Pharmaceuticals, Inc. (US) | 2011-09-14 | — | — | EP | disclosed |