SCHEMBL24119166

SCHEMBL24119166

Cc1coc2c1C(=O)C(=O)c1cc(F)ccc1-2

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 6/20 0.72
POR P16435 6/20 0.72
EED O75530 5/20 0.51
SUZ12 Q15022 5/20 0.51
EZH2 Q15910 5/20 0.51
MAPT P10636 3/20 0.51
CES2 O00748 2/20 0.51
POLB P06746 2/20 0.51
CES1 P23141 2/20 0.51
PTPN6 P29350 2/20 0.51
PTPN11 Q06124 2/20 0.51
HIF1A Q16665 2/20 0.51
NSD1 Q96L73 2/20 0.51
EPAS1 Q99814 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
KDM1A O60341 1/20 0.51
BLM P54132 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
IDO1 P14902 7/20 0.46
TDO2 P48775 6/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5940235 0.84 NQO1 (1.00) NQO1POREEDSUZ12EZH2
SCHEMBL28845339 0.80 NQO1 (1.00) NQO1POREEDSUZ12EZH2
SCHEMBL5940262 0.78 NQO1 (0.68) NQO1POREEDSUZ12EZH2
SCHEMBL5940497 0.78 NQO1 (1.00) NQO1POREEDSUZ12EZH2
SCHEMBL24119167 0.73 NQO1 (0.68) NQO1POREEDSUZ12EZH2
SCHEMBL27697021 0.70 ELANE (0.47) NQO1PORMAPTTDP1ALDH1A1
SCHEMBL14417735 0.69 EED (0.71) NQO1POREEDSUZ12EZH2
SCHEMBL19104646 0.68 MALT1 (0.43) MAPTALDH1A1KMT2AAPAF1LMNA
SCHEMBL9672767 0.68 PGR (0.50) ALDH1A1HSP90AA1MALT1
SCHEMBL8189008 0.68 NQO1 (0.75) NQO1POREEDSUZ12EZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210395283-A1 COMPOUND, COMPLEX, PREPARATION METHOD THEREOF, AND USE THEREOF JIANGSU OXIRANCHEM CO., LTD. (CN) 2021-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395283-A1 COMPOUND, COMPLEX, PREPARATION METHOD THEREOF, AND USE THEREOF NOP10, C9, RPP30 NQO1 214/4885POR 273/4885EED 3375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.