SCHEMBL24121985

SCHEMBL24121985

Cc1cc2snc(C)c2nn1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7922387 0.68 CCR1 (0.43) GRM4
SCHEMBL24121941 0.67 KDM4E (0.31)
SCHEMBL22224007 0.65 KDM4E (0.33)
SCHEMBL7919450 0.65 CCR1 (0.46)
SCHEMBL7920618 0.64 UHRF1 (0.34) GRM4
SCHEMBL16417538 0.61 GRM4 (0.34) GRM4
SCHEMBL24122080 0.61 CHRM4 (0.32)
SCHEMBL22224006 0.61 GRM4 (0.31) GRM4
SCHEMBL24756696 0.58 CLK1 (0.33) GRM4
SCHEMBL7377972 0.58 GRM4 (0.38) GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021254493-A1 CYCLIC COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF 上海翊石医药科技有限公司 2021-12-23 WO disclosed