Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24016395 | 0.80 | CCR1 (0.46) | CHRM4 | |
| SCHEMBL16541496 | 0.80 | CCR1 (0.48) | CHRM4 | |
| SCHEMBL862484 | 0.74 | — | — | |
| SCHEMBL24122086 | 0.74 | CYP2A6 (0.43) | — | |
| SCHEMBL24122148 | 0.74 | CYP1A2 (0.36) | — | |
| SCHEMBL16421707 | 0.74 | YTHDC1 (0.60) | YTHDC1YTHDF2 | |
| SCHEMBL24122177 | 0.74 | CHRM4 (0.33) | CHRM4 | |
| SCHEMBL24121805 | 0.72 | CHRM4 (0.36) | CHRM4 | |
| SCHEMBL24183817 | 0.72 | CYP2A6 (0.42) | — | |
| SCHEMBL8082857 | 0.72 | ADORA2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021254493-A1 | CYCLIC COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2021-12-23 | — | — | WO | disclosed |