Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12615653 | 0.65 | DYRK1A (0.47) | PDPK1ADORA2AADORA2BDYRK1A | |
| SCHEMBL24122188 | 0.64 | ADORA2A (0.48) | PDPK1ADORA2AADORA2BDYRK1A | |
| SCHEMBL24121978 | 0.60 | PDPK1 (0.34) | PDPK1ADORA2AADORA2BDYRK1A | |
| SCHEMBL24121974 | 0.59 | PDPK1 (0.46) | PDPK1ADORA2AADORA2BDYRK1A | |
| SCHEMBL24122181 | 0.59 | — | — | |
| SCHEMBL31736007 | 0.58 | NPY5R (0.34) | PDPK1ADORA2AADORA2BDYRK1A | |
| SCHEMBL24122083 | 0.57 | PDPK1 (0.35) | PDPK1ADORA2AADORA2BDYRK1A | |
| SCHEMBL31194340 | 0.57 | YTHDC1 (0.38) | PDPK1ADORA2AADORA2BDYRK1A | |
| SCHEMBL24122165 | 0.57 | CCR1 (0.45) | PDPK1ADORA2AADORA2B | |
| SCHEMBL24122179 | 0.56 | DYRK1A (0.39) | ADORA2AADORA2BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021254493-A1 | CYCLIC COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2021-12-23 | — | — | WO | disclosed |