Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.67 |
| ▸ | MEN1 | O00255 | 9/20 | 0.67 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.67 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.62 |
| ▸ | FGB | P02675 | 1/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.62 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.62 |
| ▸ | PLEC | Q15149 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124279 | 0.92 | KMT2A (0.65) | KMT2AMEN1GPR27PRMT1USP2 | |
| SCHEMBL30522656 | 0.92 | KMT2A (0.65) | KMT2AMEN1GPR27PRMT1USP2 | |
| SCHEMBL25926127 | 0.89 | KMT2A (0.68) | KMT2AMEN1GPR27PRMT1USP2 | |
| SCHEMBL24124285 | 0.88 | KMT2A (0.56) | KMT2AMEN1GPR27PRMT1ALDH1A1 | |
| SCHEMBL24124268 | 0.86 | KMT2A (0.61) | KMT2AMEN1GPR27USP2ALDH1A1 | |
| SCHEMBL12010897 | 0.86 | KMT2A (0.91) | KMT2AMEN1GPR27PRMT1USP2 | |
| SCHEMBL12010895 | 0.84 | KMT2A (0.83) | KMT2AMEN1GPR27PRMT1USP2 | |
| SCHEMBL12010900 | 0.83 | KMT2A (0.81) | KMT2AMEN1GPR27PRMT1USP2 | |
| SCHEMBL27180159 | 0.83 | MAPT (0.76) | KMT2AMEN1GPR27ALDH1A1PKM | |
| SCHEMBL24124292 | 0.83 | KMT2A (0.55) | KMT2AMEN1GPR27MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-08-03 | — | — | US | disclosed |
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-08-03 | — | — | US | disclosed |
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-08-03 | — | — | US | disclosed |
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | BCL6, SOX18, BCL3 | KMT2A 578/4885MEN1 2558/4885GPR27 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.