SOX18

Transcription factor SOX-18 · P35713 · SOX18 on Sugi Atlas →

427 patent compounds predicted against SOX18, 335 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL20333017 SCHEMBL20333017 1.00 1/20
SCHEMBL26638944 SCHEMBL26638944 0.73 1/20
SCHEMBL21530605 SCHEMBL21530605 0.70 1/20
SCHEMBL20332761 SCHEMBL20332761 0.70 1/20
SCHEMBL20332766 SCHEMBL20332766 0.70 1/20
SCHEMBL26638875 SCHEMBL26638875 0.69 1/20
SCHEMBL26744430 SCHEMBL26744430 0.69 1/20
SCHEMBL574679 SCHEMBL574679 0.67 1/20
SCHEMBL20332765 SCHEMBL20332765 0.67 1/20
SCHEMBL26745727 SCHEMBL26745727 0.63 1/20
SCHEMBL20771694 SCHEMBL20771694 0.58 1/20
SCHEMBL12249375 SCHEMBL12249375 0.57 1/20
SCHEMBL8702966 SCHEMBL8702966 0.56 1/20
SCHEMBL16113740 SCHEMBL16113740 0.56 1/20
SCHEMBL26744786 SCHEMBL26744786 0.55 1/20
SCHEMBL932837 SCHEMBL932837 0.55 1/20
SCHEMBL2129140 SCHEMBL2129140 0.55 1/20
SCHEMBL5202410 SCHEMBL5202410 0.55 1/20
SCHEMBL11868931 SCHEMBL11868931 0.55 1/20
SCHEMBL16870672 SCHEMBL16870672 0.55 1/20

Clinical trials — most relevant to SOX18 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Mechanisms of Lipodystrophy in HIV-Infected Pateints PHASE4COMPLETED
A Randomized Control Trial to Evaluate the Efficacy of Autologous Blood Injection Versus Local Corticosteroid Injection for Treatment of Lateral Epicondylitis PHASE2/PHASE3COMPLETED
New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia PHASE2RECRUITING
Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer PHASE1/PHASE2SUSPENDED
SUTENT (SUNITINIB, SU11248)in Patients With Recurrent or Progressive Glioblastoma Multiforme PHASE2UNKNOWN
Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer PHASE2COMPLETED
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure PHASE2COMPLETED
Open-label Trial of SUBA™-Itraconazole (SUBA-Cap) in Subjects With Basal Cell Carcinoma Nevus Syndrome (BCCNS) PHASE2COMPLETED
Stem Cell Treatment for Regeneration of the Rotator Cuff (Lipo-Cuff Study) PHASE1ENROLLING_BY_INVITATION
EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma PHASE1COMPLETED
Treatment Duration Increment and Pharmacodynamic Study of CX-4945 in Patients With Basal Cell Carcinoma (BCC) PHASE1COMPLETED
A Clinical Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Injection (CNCT19) in the Treatment of Cluster of Differentiation 19 (CD19) Positive Relapsed or Refractory B Cell Malignancies EARLY_PHASE1UNKNOWN
Predictive Value of E-cadherin, β-catenin and SOX4 in Recurrence and/or Progression of Non-muscle Invasive Urinary Bladder Transitional Cell Carcinoma. A Retrospective Study nanCOMPLETED
Exploring the Role of Serum Methylmalonic Acid (MMA) in Breast Cancer nanCOMPLETED
Micro RNA Levels in NAFLD nanUNKNOWN
Patient-derived Glioma Stem Cell Organoids nanACTIVE_NOT_RECRUITING
Molecular Genetic Epidemiology of Three Cardiac Defects -SCOR in Pediatric Cardiovascular Disease nanCOMPLETED
X-chromosome Inactivation, Epigenetics and the Transcriptome nanCOMPLETED
Genetic Clues to Chordoma Etiology: A Protocol to Identify Sporadic Chordoma Patients for Studies of Cancer-Susceptibility Genes nanACTIVE_NOT_RECRUITING
Chromosomal and Morphological Structure of Mature and Immature Male Germ Cells and Recognition of IL-18 in Testicular Tissue of Azoospermic Men nanCOMPLETED
Derivation of New Human Embryonic Stem Cell Lines: Identification of Instructive Factors for Germ Cells Development nanUNKNOWN
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
Cryopreservation of Prepubertal Testicular Tissue for Preservation of Fertility in Young Boys With Cancer nanRECRUITING
Role of HIF-1α in Skeletal Muscle Aging nanUNKNOWN
Use Of Oral Itraconazole In Patients With Locally Limited Basocellular Carcinoma Of Skin. nanUNKNOWN
Natural History of Spinocerebellar Ataxia Type 7 (SCA7) nanRECRUITING
Immunophenotyping and Xist Gene in AML nanUNKNOWN
RORC Genetic Polymorphism of Rheumatoid Arthritis nanCOMPLETED
COPENHAGEN Minipuberty Study nanUNKNOWN
MR Elastography in Intracranial Lesions: Feasibility & Accuracy nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a SOX18 binder may also engage these)

ProteinNameSimilarity
Q9QY14 0.993 Q9QY14 →
P43680 0.993 P43680 →
Q13461 0.992 Q13461 →
Q63250 0.991 Q63250 →
Q05215 0.991 Q05215 →
O15522 0.989 O15522 →
Q9ET58 0.989 Q9ET58 →
Q9C009 0.989 Q9C009 →
A1YF08 0.988 A1YF08 →
O60548 0.988 O60548 →
Q9WUF2 0.988 Q9WUF2 →
O35767 0.988 O35767 →
Q00911 0.988 Q00911 →
P52952 0.987 P52952 →
Q60843 0.987 Q60843 →
Q9GLW0 0.987 Q9GLW0 →
P52945 0.987 P52945 →
A7MB34 0.986 A7MB34 →
P17483 0.986 P17483 →
Q9H2A3 0.986 Q9H2A3 →
A6NEQ2 0.986 A6NEQ2 →
Q9GL32 0.986 Q9GL32 →
A8MYZ6 0.986 A8MYZ6 →
O15370 0.986 O15370 →
O70220 0.986 O70220 →
Q9Y5W3 0.986 Q9Y5W3 →
Q5PQP0 0.986 Q5PQP0 →
Q15270 0.985 Q15270 →
Q8WY41 0.985 Q8WY41 →
Q9NP08 0.985 Q9NP08 →