Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24125062 | 1.00 | HDAC1 (0.56) | HDAC1HDAC8HDAC6TP53RAB9A | |
| SCHEMBL24125034 | 0.92 | KMT2A (0.56) | HDAC1HDAC8HDAC6TP53RAB9A | |
| SCHEMBL24125112 | 0.92 | KMT2A (0.56) | HDAC1HDAC8HDAC6TP53RAB9A | |
| SCHEMBL24124158 | 0.91 | RAB9A (0.59) | HDAC1HDAC8HDAC6TP53RAB9A | |
| SCHEMBL24124870 | 0.91 | TP53 (0.62) | HDAC1HDAC8HDAC6TP53RAB9A | |
| SCHEMBL25920723 | 0.91 | RAB9A (0.62) | HDAC1HDAC8HDAC6TP53RAB9A | |
| SCHEMBL24125086 | 0.91 | RAB9A (0.62) | HDAC1HDAC8HDAC6TP53RAB9A | |
| SCHEMBL24125219 | 0.91 | RAB9A (0.59) | HDAC1HDAC8HDAC6TP53RAB9A | |
| SCHEMBL24125099 | 0.91 | RAB9A (0.62) | HDAC1HDAC8HDAC6TP53RAB9A | |
| SCHEMBL25921712 | 0.91 | SMN1; SMN2 (0.58) | HDAC1HDAC8HDAC6TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |