Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24931289 | 0.82 | HTT (0.30) | HTT | |
| SCHEMBL3161069 | 0.73 | — | — | |
| SCHEMBL3161908 | 0.73 | HTT (0.49) | HTT | |
| SCHEMBL3161901 | 0.73 | HTT (0.49) | HTT | |
| SCHEMBL20625465 | 0.72 | XDH (0.30) | — | |
| SCHEMBL24717114 | 0.68 | HTT (0.30) | HTT | |
| SCHEMBL403843 | 0.64 | MEN1 (0.32) | — | |
| SCHEMBL2936179 | 0.63 | — | — | |
| SCHEMBL16321601 | 0.62 | — | — | |
| SCHEMBL15897095 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257614-A1 | HETEROCYCLIC INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2021-12-23 | — | — | WO | disclosed |