Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9921218 | 0.83 | TP53 (0.50) | ALDH1A1TP53L3MBTL1GAATSHR | |
| SCHEMBL24010106 | 0.82 | ALDH1A1 (0.38) | ALDH1A1TP53L3MBTL1GAATSHR | |
| SCHEMBL10265740 | 0.80 | KDM4E (0.44) | ALDH1A1TP53L3MBTL1GAATSHR | |
| SCHEMBL24931276 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL16508914 | 0.78 | CA1 (0.42) | ALDH1A1TP53L3MBTL1GAATSHR | |
| SCHEMBL24129384 | 0.78 | — | — | |
| SCHEMBL15870713 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TP53L3MBTL1GAATSHR | |
| SCHEMBL12228512 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TP53L3MBTL1GAATSHR | |
| SCHEMBL13252481 | 0.76 | ALDH1A1 (0.45) | ALDH1A1TP53L3MBTL1GAATSHR | |
| SCHEMBL10289418 | 0.75 | TP53 (0.43) | ALDH1A1TP53L3MBTL1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220402-A1 | ENPP1 MODULATORS AND PRODUCTS AND USES THEREOF | GOSSAMER BIO SERVICES, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2021257614-A1 | HETEROCYCLIC INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2021-12-23 | — | — | WO | disclosed |