Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 12/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412977 | 1.00 | ABCB1 (0.39) | ABCB1MKNK1MKNK2ABCC1CYP11B1 | |
| SCHEMBL2410189 | 0.91 | MKNK1 (0.41) | ABCB1MKNK1MKNK2ABCC1CYP11B1 | |
| SCHEMBL2410194 | 0.91 | MKNK1 (0.41) | ABCB1MKNK1MKNK2ABCC1CYP11B1 | |
| SCHEMBL2412587 | 0.88 | ERN1 (0.38) | ABCB1MKNK1MKNK2ABCC1CYP11B1 | |
| SCHEMBL2412590 | 0.88 | ERN1 (0.38) | ABCB1MKNK1MKNK2ABCC1CYP11B1 | |
| SCHEMBL2411969 | 0.86 | CYP17A1 (0.40) | ABCB1ABCC1CYP11B1CYP11B2PDK2 | |
| SCHEMBL2411966 | 0.86 | CYP17A1 (0.40) | ABCB1ABCC1CYP11B1CYP11B2PDK2 | |
| SCHEMBL314886 | 0.84 | CYP11B2 (0.37) | MKNK1MKNK2CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL2419641 | 0.84 | MKNK1 (0.41) | MKNK1MKNK2CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL2419644 | 0.84 | MKNK1 (0.41) | MKNK1MKNK2CYP11B1CYP11B2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013010-B2 | 5-thioxylopyranose compounds | LABORATOIRES FOURNIER S.A. (FR) | 2011-09-06 | — | — | US | disclosed |
| US-20090186840-A1 | 5-Thioxylopyranose Compounds | LABORATOIRES FOURNIER S.A (FR) | 2009-07-23 | — | — | US | disclosed |
| EP-2066681-A1 | NEW DERIVATIVES OF 5-THIOXILOPYRANOSE | LABORATOIRES FOURNIER SA (FR) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008037923-A1 | NEW DERIVATIVES OF 5-THIOXILOPYRANOSE | LABORATOIRES FOURNIER S.A. (FR) | 2008-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186840-A1 | 5-Thioxylopyranose Compounds | TPMT, PNPO, CYP3A5 | ABCB1 867/4885MKNK1 2501/4885MKNK2 2929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.