Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Reserpine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A2 known ✓ | Q05940 | 1/20 | 0.99 |
| ▸ | MEN1 | O00255 | 13/20 | 0.99 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.99 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.99 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.99 |
| ▸ | TSHR | P16473 | 6/20 | 0.99 |
| ▸ | HBB | P68871 | 5/20 | 0.99 |
| ▸ | MAPT | P10636 | 5/20 | 0.99 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.99 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.99 |
| ▸ | USP2 | O75604 | 4/20 | 0.99 |
| ▸ | CASP1 | P29466 | 4/20 | 0.99 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.99 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.99 |
| ▸ | CASP7 | P55210 | 3/20 | 0.99 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.99 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.99 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.99 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.99 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.99 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Reserpine SCHEMBL1172973 | 0.99 | MEN1 (1.00) | MEN1KMT2AKDM4ETDP1TSHR | |
| Reserpine SCHEMBL20402680 | 0.99 | MEN1 (1.00) | MEN1KMT2AKDM4ETDP1TSHR | |
| Reserpine SCHEMBL15385127 | 0.99 | MEN1 (1.00) | MEN1KMT2AKDM4ETDP1TSHR | |
| Reserpine SCHEMBL14379427 | 0.99 | MEN1 (1.00) | MEN1KMT2AKDM4ETDP1TSHR | |
| Reserpine SCHEMBL12732449 | 0.99 | MEN1 (1.00) | MEN1KMT2AKDM4ETDP1TSHR | |
| Reserpine SCHEMBL8262666 | 0.99 | MEN1 (1.00) | MEN1KMT2AKDM4ETDP1TSHR | |
| Reserpine SCHEMBL4562878 | 0.99 | MEN1 (1.00) | MEN1KMT2AKDM4ETDP1TSHR | |
| Reserpine SCHEMBL5372164 | 0.99 | MEN1 (1.00) | MEN1KMT2AKDM4ETDP1TSHR | |
| Reserpine SCHEMBL22002247 | 0.99 | MEN1 (1.00) | MEN1KMT2AKDM4ETDP1TSHR | |
| Isoreserpine SCHEMBL731599 | 0.99 | MEN1 (1.00) | MEN1KMT2AKDM4ETDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2855 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118311276-A | Method for identifying species of human prothrombin complex | 山东省食品药品检验研究院 | 2024-07-09 | — | — | CN | claimed |
| CN-115032318-B | Liquid chromatographic analysis method for detecting content of 3- (N-nitrosomethylamino) propionitrile | 中国食品药品检定研究院 | 2024-07-05 | — | — | CN | claimed |
| CN-118067908-B | Targeted data analysis method for non-targeted metabonomics research | 长春中医药大学 | 2024-07-05 | — | — | CN | claimed |
| CN-118191129-A | Fingerprint construction method of traditional Chinese medicine composition containing rheum officinale and application of fingerprint construction method | 湖南易能生物医药有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118067908-A | Targeted data analysis method for non-targeted metabonomics research | 长春中医药大学 | 2024-05-24 | — | — | CN | claimed |
| CN-117969730-A | Method for screening antioxidant active ingredients from Gu Shu Ning formula | 玉林市中西医结合骨科医院 | 2024-05-03 | — | — | CN | claimed |
| CN-117965681-A | Method for detecting activities of multiple biological enzymes in Daqu | 贵州习酒股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| WO-2024087945-A1 | QUALITATIVE AND QUANTITATIVE MEASUREMENT METHOD FOR XIASANGJU GRANULES | 广州白云山星群(药业)股份有限公司 | 2024-05-02 | — | — | WO | claimed |
| CN-117890521-A | Analysis method of triterpene compounds in Rosa roxburghii original juice | 贵州习酒股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117825589-A | Method for detecting N1-methyl-pseudouridine modified abundance in RNA by liquid chromatography-mass spectrometry or liquid chromatography | 中国农业科学院生物技术研究所 | 2024-04-05 | — | — | CN | claimed |
| CN-104330482-A | Method utilizing HPLC to simultaneously measure 17 characteristic components in tea | HANGZHOU YUHANG DISTR QUALITY METERING MONITORING CT | 2015-02-04 | — | — | CN | claimed |
| CN-101368952-B | ELISA adsorption analysis method for measuring clenobuterol hydrochloride content in milk, pork liver, chicken liver and animal feed | UNIV SICHUAN | 2012-07-04 | — | — | CN | claimed |
| CN-101078723-B | ELISA method for determining sudan 1 in food | UNIV SICHUAN | 2011-11-16 | — | — | CN | claimed |
| US-7759500-B2 | 2-(N-methyl-propanamine)-3-(2-naphthol)thiophene, an impurity of duloxetine hydrochloride | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2010-07-20 | — | — | US | claimed |
| CN-101726590-A | Enzyme-linked immunosorbent assay for measuring content of lincomycin hydrochloride in food | UNIV SICHUAN | 2010-06-09 | — | — | CN | claimed |
| CN-101368952-A | ELISA adsorption analysis method for measuring clenobuterol hydrochloride content in milk, pork liver, chicken liver and animal feed | UNIV SICHUAN (CN) | 2009-02-18 | — | — | CN | claimed |
| CN-101358978-A | ELISA adsorption analysis method for detecting monoclonal antibodies of sudan red NO.1 in foodstuff | UNIV SICHUAN (CN) | 2009-02-04 | — | — | CN | claimed |
| CN-101078723-A | ELISA method for determining sudan 1 in food | UNIV SICHUAN (CN) | 2007-11-28 | — | — | CN | claimed |
| US-20070191472-A1 | 2-(N-methyl-propanamine)-3-(2-naphthol)thiophene, an impurity of duloxetine hydrochloride | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-08-16 | — | — | US | claimed |
| US-20060252932-A1 | Isolated bis-linezolid, preparation thereof, and its use as a reference standard | ENTIRE INTEREST | 2006-11-09 | — | — | US | claimed |