Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 11/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413287 | 1.00 | BRD4 (0.36) | BRD4CREBBPHCRTR1HCRTR2PIK3CD | |
| SCHEMBL314386 | 0.88 | BRD4 (0.37) | BRD4CREBBPGAA | |
| SCHEMBL314387 | 0.88 | BRD4 (0.37) | BRD4CREBBPGAA | |
| SCHEMBL2414404 | 0.81 | WNT1 (0.37) | BRD4CREBBPPRMT5WDR77 | |
| SCHEMBL2414409 | 0.81 | WNT1 (0.37) | BRD4CREBBPPRMT5WDR77 | |
| SCHEMBL2410510 | 0.79 | IKBKB (0.33) | — | |
| SCHEMBL2410514 | 0.79 | IKBKB (0.33) | — | |
| SCHEMBL2414199 | 0.79 | BRD4 (0.35) | BRD4CREBBPPRMT5WDR77SYK | |
| SCHEMBL2414203 | 0.79 | BRD4 (0.35) | BRD4CREBBPPRMT5WDR77SYK | |
| SCHEMBL2415464 | 0.78 | PRMT5 (0.36) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013010-B2 | 5-thioxylopyranose compounds | LABORATOIRES FOURNIER S.A. (FR) | 2011-09-06 | — | — | US | disclosed |
| US-20090186840-A1 | 5-Thioxylopyranose Compounds | LABORATOIRES FOURNIER S.A (FR) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186840-A1 | 5-Thioxylopyranose Compounds | TPMT, PNPO, CYP3A5 | BRD4 4110/4885CREBBP 4100/4885HCRTR1 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.