Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30644655 | 1.00 | LMNA (0.50) | LMNAKMT2APOLBALDH1A1THRB | |
| SCHEMBL10036857 | 0.90 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1THRB | |
| SCHEMBL2338780 | 0.90 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1THRB | |
| SCHEMBL8647178 | 0.90 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1THRB | |
| SCHEMBL5148124 | 0.90 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1THRB | |
| SCHEMBL21762059 | 0.90 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1THRB | |
| SCHEMBL19477779 | 0.90 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1THRB | |
| SCHEMBL22537923 | 0.90 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1THRB | |
| SCHEMBL20643514 | 0.90 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1THRB | |
| SCHEMBL19477874 | 0.90 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11207343-B2 | Compositions and therapeutic methods | AYUVIS RESEARCH, INC. (US) | 2021-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11207343-B2 | Compositions and therapeutic methods | RB1, TNF, FLT1 | LMNA 3709/4885KMT2A 4040/4885POLB 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.