Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25138400 | 0.98 | HTT (0.44) | THRBNPC1LMNACYP3A4HTT | |
| SCHEMBL25138398 | 0.98 | HTT (0.44) | THRBNPC1LMNACYP3A4HTT | |
| SCHEMBL25138399 | 0.98 | THRB (0.43) | THRBNPC1LMNACYP3A4HTT | |
| SCHEMBL25138384 | 0.98 | HTT (0.44) | THRBNPC1LMNACYP3A4HTT | |
| SCHEMBL25138375 | 0.97 | THRB (0.43) | THRBNPC1LMNACYP3A4HTT | |
| SCHEMBL29343551 | 0.97 | THRB (0.46) | THRBNPC1LMNACYP3A4HTT | |
| SCHEMBL19978527 | 0.91 | THRB (0.55) | THRBNPC1LMNACYP3A4HTT | |
| SCHEMBL14365182 | 0.91 | THRB (0.55) | THRBNPC1LMNACYP3A4HTT | |
| SCHEMBL14426396 | 0.90 | KMT2A (0.45) | THRBNPC1LMNACYP3A4HTT | |
| SCHEMBL20672698 | 0.90 | THRB (0.49) | THRBNPC1LMNACYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11208596-B2 | Optical film, polarizing plate, and image display device | FUJIFILM CORPORATION (JP) | 2021-12-28 | — | — | US | disclosed |