Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989217 | 0.80 | LMNA (0.51) | LMNACA12CA1CA2CA3 | |
| SCHEMBL2372821 | 0.79 | LMNA (0.62) | LMNACA12CA1CA2CA3 | |
| SCHEMBL21028420 | 0.77 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL24795821 | 0.76 | DAO (0.52) | LMNACA12CA1CA2CA3 | |
| SCHEMBL12767421 | 0.76 | LMNA (0.59) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31061939 | 0.76 | LMNA (0.59) | LMNACA12CA1CA2CA3 | |
| SCHEMBL8371409 | 0.75 | LMNA (0.58) | LMNACA12CA1CA2CA3 | |
| SCHEMBL692195 | 0.75 | LMNA (0.58) | LMNACA12CA1CA2CA3 | |
| SCHEMBL5315883 | 0.75 | LMNA (0.58) | LMNACA12CA1CA2CA3 | |
| SCHEMBL29361971 | 0.75 | LMNA (0.58) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928771-A1 | PHARMACEUTICAL COMPOSITIONS OF 1,2-BENZISOXAZOLE-3-METHANESULFONAMIDE | Laboratorios Lesvi, S.L. (ES) | 2021-12-29 | — | — | EP | disclosed |