Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.52 |
| ▸ | CA6 | P23280 | 5/20 | 0.52 |
| ▸ | CA7 | P43166 | 5/20 | 0.52 |
| ▸ | CA9 | Q16790 | 5/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA4 | P22748 | 4/20 | 0.52 |
| ▸ | CA5A | P35218 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CA3 | P07451 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CASP2 | P42575 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1234728 | 0.88 | CA12 (0.55) | CA12CA6CA7CA9CA14 | |
| SCHEMBL9064146 | 0.88 | CA12 (0.55) | CA12CA6CA7CA9CA14 | |
| SCHEMBL7594298 | 0.83 | ALDH1A1 (0.44) | CA12CA6CA7CA9CA14 | |
| SCHEMBL26633359 | 0.82 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL27383862 | 0.78 | CA12 (0.55) | CA12CA6CA7CA9CA14 | |
| SCHEMBL11427381 | 0.76 | CA12 (0.46) | CA12CA6CA7CA9CA14 | |
| Trientine SCHEMBL8987399 | 0.74 | CA12 (0.50) | CA12CA6CA7CA9CA14 | |
| SCHEMBL9700675 | 0.73 | CYP2C19 (0.58) | CA12CA6CA7CA9CA14 | |
| SCHEMBL27574922 | 0.73 | CYP2C9 (0.41) | CA12CA6CA7CA9CA14 | |
| Trientine SCHEMBL2413625 | 0.73 | CA12 (0.85) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706503-B1 | METHOD FOR DETECTING PrP USING A MOLECULE CONTAINING AT LEAST ONE POSITIVE CHARGE AND/OR AT LEAST ONE OSIDIC BOND AND A LIGAND OTHER THAN A PROTEINIC LIGAND | BIOMERIEUX SA (FR) | 2011-09-07 | — | — | EP | claimed |