Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SLC9A3 | P48764 | 3/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15627255 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDHTTPOLBHSD17B10 | |
| SCHEMBL27306806 | 0.93 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDHTTPOLBHSD17B10 | |
| SCHEMBL16118174 | 0.92 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDHTTPOLBHSD17B10 | |
| SCHEMBL24136297 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDHTTPOLBHSD17B10 | |
| SCHEMBL14750406 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDHTTPOLBHSD17B10 | |
| SCHEMBL22134362 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDHTTPOLBHSD17B10 | |
| SCHEMBL18430819 | 0.89 | SMN1; SMN2 (0.35) | SMN1; SMN2HPGDHTTPOLBHSD17B10 | |
| SCHEMBL25100591 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDHTTPOLBHSD17B10 | |
| SCHEMBL14750411 | 0.89 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTPOLBHSD17B10 | |
| SCHEMBL22134405 | 0.89 | DRD2 (0.37) | SMN1; SMN2HPGDHTTPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11208451-B2 | Protein and protein conjugate for diabetes treatment, and applications thereof | ADDA BIOTECH INC. | 2021-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11208451-B2 | Protein and protein conjugate for diabetes treatment, and applications thereof | GLP1R, GIPR, IAPP | SMN1; SMN2 2613/4885HPGD 3590/4885HTT 2455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.