Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136486 | 1.00 | GRIN2B (0.60) | GRIN2BGRIN1 | |
| SCHEMBL24270883 | 0.82 | GRIN2B (0.43) | GRIN2BGRIN1 | |
| SCHEMBL24136447 | 0.81 | GRIN2B (0.45) | GRIN2BGRIN1 | |
| SCHEMBL20090983 | 0.81 | GRIN2B (0.45) | GRIN2BGRIN1 | |
| SCHEMBL24136387 | 0.80 | GRIN1 (0.68) | GRIN2BGRIN1 | |
| SCHEMBL24136436 | 0.79 | ESR1 (0.46) | GRIN2BGRIN1 | |
| SCHEMBL24136379 | 0.79 | GRIN2B (0.63) | GRIN2BGRIN1 | |
| SCHEMBL22239314 | 0.79 | GRIN2B (0.63) | GRIN2BGRIN1 | |
| SCHEMBL24136435 | 0.78 | GRIN2B (0.45) | GRIN2BGRIN1 | |
| SCHEMBL24136355 | 0.78 | GRIN2B (0.45) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3683207-B1 | N-ALKYLARYL-5-OXYARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2B | CADENT THERAPEUTICS INC (US) | 2021-12-29 | — | — | EP | disclosed |